Analysis of system capacity and spectral efficiency of fixed-grid network

In this article, the performance of a fixed grid network is examined for various modulation formats to estimate the system's capacity and spectral efficiency. The optical In-phase Quadrature Modulator structure is used to build a fixed grid network modulation, and the homodyne detection approach is used for the receiver. Data multiplexing is accomplished using the Polarization Division Multiplexed technology. 100 Gbps, 150 Gbps, and 200 Gbps data rates are transmitted under these circumstances utilizing various modulation formats. Various pre-processing and signal recovery steps are explained by using modern digital signal processing systems. The achieved spectrum efficiencies for PM-QPSK, PM-8 QAM, and PM-16 QAM, respectively, were 2, 3, and 4 bits/s/Hz. Different modulation like PM-QPSK, PM-8-QAM, and PM-16-QAM each has system capacities of 8-9, 12-13.5, and 16-18 Tbps and it reaches transmission distances of 3000, 1300, and 700 kilometers with acceptable Bit Error Rate less than equal to 2*10-3 respectively. Peak optical power for received signal detection and full width at half maximum is noted for the different modulations under a fixed grind network

Impact of magnetic resonance imaging on arthroscopic surgeries of knee joint

Background: Though magnetic resonance imaging (MRI) is popular as a diagnostic tool, questions arise regarding imaging when clinical diagnosis of most internal derangements of knee can be done. Treatment of meniscal and anterior cruciate ligament (ACL) injuries usually involves arthroscopic surgery after MRI. But accurately performed examination with positive signs alone will be justified for arthroscopy directly without MRI. The aims and objectives of this study are to assess the impact of MRI in selecting or excluding cases which genuinely require an arthroscopic surgery. To know whether routine MRI is required pre-operatively in all cases with positive clinical findings.Methods: 60 cases underwent clinical examination of affected knee and a preliminary diagnosis was made. Further they were subjected to MRI. Results of arthroscopy were considered as definitive diagnosis and results of clinical examination and MRI were judged accordingly.Results: Of 60 patients, examination revealed 85% accuracy, 82% sensitivity, 89% specificity for ACL injuries. For medial meniscus 58% accuracy, 66% sensitivity, 48% specificity. For lateral meniscus 55% accuracy, 58% sensitivity, 50% specificity. MRI revealed 73% accuracy, 82% sensitivity, 63% specificity for ACL injuries. For medial meniscus 63% accuracy, 90% sensitivity, 39% specificity. For lateral meniscus 62% accuracy, 79% sensitivity, 50% specificity.Conclusions: Clinical examination is more sensitive, specific and accurate in diagnosis of ACL. MRI is more sensitive but less specific for meniscal injuries. Clinical examination for cruciate injuries can surpass the MRI findings. Arthroscopy can be performed without MRI in single lesion injuries. However, MRI will play a role in meniscal injuries or doubtful cases

IN VITRO ANTIOXIDANT, ANTIMICROBIAL AND ADMET STUDY OF NOVEL FURAN/BENZOFURAN C-2 COUPLED QUINOLINE HYBRIDS

Objectives: Synthesis of novel 2-(benzofuran-2-yl) and 2-(furan-2-yl) quinoline-4- carboxylates and their [2-(1-benzofuran-2-yl) quinolin-4-yl] methanol, [2-(1-furan-2-yl) quinolin-4-yl] methanol and its derivatives for antioxidant, antimicrobial and ADMET study.Methods: Synthesis was carried with conventional method and the structures were confirmed by IR, 1H NMR, 13C NMR and mass spectral analysis. The antioxidant activity was performed by DPPH and H2O2 radical scavenging method. Antimicrobial investigation was established by cup plate and food poison technique. The in silico absorption, distribution, metabolism, excretion and toxicity (ADMET) study of the drug was carried out in ACD/lab-2.Results: The antioxidant activity results revealed that, compounds 4b-c, 5a-b, 10c and 10f exhibited good DPPH radical and hydrogen peroxide scavenging activity. The antibacterial results revealed that, compounds 4c, 5a-b, 10b, 10d and 10f exhibited good activity against Escherichia coli, Klebsiella pneumonia and Salmonella typhimurium. Further, the antifungal activity results showed that, compounds 4c, 5c and 10c-e were showing good activity against Aspergillus flavus and Candida neoformans.  The mean value of P<0.05 were considered to be statistically significant. The ADMET results revealed that compounds emerged as a potential candidate for antioxidant and antimicrobial agents.Conclusion: The study reveals that compounds containing furan/benzofuran coupled heterocycles are play the important role for activity as they possess potent antioxidant and antimicrobial agents. The in silico ADME analysis also suggesting the compounds were in acceptable range to obey the pharmacokinetic parameters.Â

The Dynamic Characteristics of a non-linear main landing gear system of an aircraft during landing

The landing gear plays a very important role during landing by absorbing the high impact energy of the aircraft. The main landing gear absorbs the bulk of the load to reduce the load experienced by both the aircraft fuselage and the nose landing gear. In this paper, a mathematical approach is used to extract the dynamic characteristics of the system. A two-degree of freedom mathematical model of the main landing gear is developed. This model is used to derive the dynamic equations of the landing gear system and to study the behaviour of main landing gear during main gear and nose gear touchdown conditions. The non-linear stiffness and damping co-efficient in an Oleo-Pneumatic shock absorber are integrated into the system to achieve a more accurate response of the system. The response of this system is established by adopting a complex modal analysis approach to account for the non-classical damping exhibited by the system. The obtained spring force, damping force and responses are reported. This work provides an alternative approach using complex modal analysis to obtain results for complex systems exhibiting non-linear characteristics

A systematic quantitative literature review of aquaculture genetic resource access and benefit sharing

The Convention on Biological Diversity provides a framework for countries to implement laws regulating the access, use and exchange of genetic resources, including how users and providers share the benefits from their use. While the international community has been preoccupied with resolving the unintended effects of access and benefit sharing (ABS) on domestication in agriculture for the past 25 years, its far-reaching consequences for global aquaculture has only recently dawned on policymakers, aquaculture producers and researchers. Using a systematic quantitative literature review methodology, we analysed the trends, biases and gaps in the ABS literature. Only 5% of the ABS literature related to the use and exchange of aquaculture genetic resources. Most of this literature related to use in developing countries or global use, but its authors were predominantly from developed countries. The literature covered a narrow range of countries (7) and regions (3), a narrow range of taxonomic groups (9) and a narrow range of uses. Given that aquaculture is the fastest growing global food production sector with products primarily from developing countries using over 580 species, there are significant gaps in aquaculture-related ABS literature. We conclude that the sector needs urgent analyses on the consequences of ABS restrictions, obligations and opportunities for its early stages of domestication and product development. We recommend priority areas for attention to ensure that rapidly evolving national ABS laws take into account the special characteristics and needs of the aquaculture sector